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This triple mechanism distinguishes it from dual-agonist peptides like tirzepatide (GLP-1/GIP) and single-agonist compounds like semaglutide (GLP-1 only), making it the most broadly acting incretin-class compound currently under clinical investigation

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doi:10.1080/15563650600811607

This dual action of promoting fat breakdown while simultaneously reducing fat storage creates the net effect of adipose tissue reduction, all occurring at the peripheral tissue level without involvement of central appetite-regulating pathways in the hypothalamus

In healthy adults, hepatic copper concentration ranges from 15 to 55 mcg per gram of dry liver weight [2]